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Genetic and Rare Diseases Information Center (GARD)

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Littoral cell angioma of the spleen


Other Names for this Disease
  • Littoral cell angioma
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Overview

Littoral cell angioma (LCA)  is a vascular tumor of the spleen. A vascular tumor is an overgrowth of blood vessels. The condition was first described in 1991. In many cases, LCA does not produce any symptoms and is found when tests are being performed for other reasons (an incidental finding). However, in some cases, individuals with LCA have an enlarged spleen (splenomegaly), abdominal pain, fever, and portal hypertension (increased pressure in the vein that carries blood from the digestive organs to the liver).[1][2] Though most reported cases of LCA have been benign, some reports have associated LCA with various other conditions including Crohn's disease, Gaucher disease, lymphoma, aplastic anemia, colon cancer, pancreatic cancer, lung cancer, and myelodysplastic syndrome.[1][2] In rare cases, the LCA itself can become cancerous. The treatment of choice is usually removal of the spleen (splenectomy).[1]
Last updated: 7/10/2015

References

  1. Gupta, P., et al.. Littoral Cell Angioma of Spleen: An Uncommon Presentation of a Rare Neoplasm. J. Clin Imaging Sci. November 30, 2012; 2:69:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551492/. Accessed 7/10/2015.
  2. Rana, N. et al.. Case Report: Littoral cell angioma of spleen. Indian J Radiol Imaging. Aug 19, 2009; 19(3):210-212. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766879/. Accessed 7/10/2015.
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In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Littoral cell angioma of the spleen. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Littoral cell angioma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.