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Diseases

Genetic and Rare Diseases Information Center (GARD)

Danon disease


Other Names for this Disease
  • Vacuolar cardiomyopathy and myopathy X-linked
  • X-linked vacuolar cardiomyopathy and myopathy
  • Antopol disease
  • Pseudoglycogenosis 2
  • Glycogen storage disease limited to the heart
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Cause

Newline Maker

What causes Danon disease?

Danon disease is caused by mutation in the LAMP2 gene. LAMP2 stands for “lysosomal-associated membrane protein 2.”[1][2][3]
Last updated: 3/19/2010

References
  1. Yang Z et al. Danon disease as an underrecognized cause of hypertrophic cardiomyopathy in children. Circulation. 2005;
  2. Maron BJ et al. Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA. 2009;
  3. Danon disease. Online Mendelian Inheritance in Man. March 19, 2010; http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300257. Accessed 1/1/2008.


Other Names for this Disease
  • Vacuolar cardiomyopathy and myopathy X-linked
  • X-linked vacuolar cardiomyopathy and myopathy
  • Antopol disease
  • Pseudoglycogenosis 2
  • Glycogen storage disease limited to the heart
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.