Other Names for this Disease
- Systemic sclerosis
- Scleroderma, systemic
- Progressive systemic sclerosis
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Most cases of systemic scleroderma are sporadic and are not inherited. This means the condition typically occurs in people with no history of the condition in their family. Some people with systemic scleroderma have relatives with other autoimmune disorders, and a few cases of the condition have been reported to run in families. However, the condition is not caused by a single gene that is passed on to offspring. Multiple genetic and environmental factors likely interact to put someone at an increased risk to develop the condition.
Last updated: 4/9/2014
- Systemic scleroderma. Genetics Home Reference. September, 2011; http://ghr.nlm.nih.gov/condition/systemic-scleroderma. Accessed 4/9/2014.