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Diseases

Genetic and Rare Diseases Information Center (GARD)

Pityriasis lichenoides et varioliformis acuta


Other Names for this Disease
  • Mucha-Habermann disease
  • PLEVA
Related Diseases
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Overview

Pityriasis lichenoides et varioliformis acuta (PLEVA) is the acute form of a skin condition called pityriasis lichenoides. Affected people generally develop a few to more than one hundred scaling papules which may become filled with blood and/or pus or erode into crusted red-brown spots. PLEVA generally resolves on its own within a few weeks to a few months; however, some people experience episodes of the condition on and off for years. Although PLEVA is diagnosed in people of all ages, it most commonly affects children and young adults. The exact underlying cause is unknown, but some scientists suspect that it may occur due to an exaggerated immune response or an overproduction of certain white blood cells (lymphoproliferative disorder). If treatment is necessary, recommended therapies may include oral antibiotic, sun exposure, topical steroids, immunomodulators (medications used to help regulate or normalize the immune system), phototherapy and/or systemic steroids.[1][2][3]
Last updated: 2/3/2015

References

  1. Pityriasis lichenoides. DermNet NZ. January 2015; http://dermnetnz.org/scaly/pityriasis-lichenoides.html.
  2. Mucha Habermann disease. NORD. February 2012; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/752/viewAbstract.
  3. Peter A Klein, MD. Pityriasis Lichenoides. Medscape Reference. October 2014; http://emedicine.medscape.com/article/1099078-overview.
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Basic Information

  • The British Association of Dermatologists provides an informational leaflet on pityriasis lichenoides.  Click on the British Association of Dermatologists link to view this leaflet.
  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Pityriasis lichenoides et varioliformis acuta. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Mucha-Habermann disease
  • PLEVA
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.