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Diseases

Genetic and Rare Diseases Information Center (GARD)

Pityriasis lichenoides et varioliformis acuta


Other Names for this Disease
  • Mucha-Habermann disease
  • PLEVA
Related Diseases
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Your Question

I have been diagnosed with Mucha-Haberman disease. I don't know how I contracted this disease. For a couple of years, I was very sick and couldn't seem to get well. Now my symptoms flare up occasionally but I have blisters all of the time. What causes this condition? How is it treated?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What causes pityriasis lichenoides et varioliformis acuta?

The exact underlying cause of pityriasis lichenoides et varioliformis acuta (PLEVA) is unknown. Some scientists suspect that it may occur due to an exaggerated immune response or hypersensitivity to an infection. Some of the infections that have been associated with PLEVA include:[1][2][3]
Others scientists think the condition may be a benign lymphoproliferative disorder. These conditions are characterized by an overproduction of certain white blood cells (lymphocytes) which can result in tissue and organ damage.[1][2][3]
Last updated: 2/2/2015

How might pityriasis lichenoides et varioliformis acuta be treated?

Pityriasis lichenoides et varioliformis acuta (PLEVA) often resolves on its own within several weeks to several months. Depending on the severity of the condition and the symptoms present, treatment may not be necessary.[1][3]

If treatment is indicated, there are many different therapies that have been used to treat PLEVA with varying degrees of success. These include:[1][2][3]
Unfortunately, PLEVA may not always respond to treatment and relapses often occur when treatment is discontinued.[1]
Last updated: 2/2/2015

References
Other Names for this Disease
  • Mucha-Habermann disease
  • PLEVA
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.