Other Names for this Disease
lymphatic system. In general, lymphatic malformations are categorized into macrocystic, microcystic, or combined depending on the size of the cysts; they are also classified in superficial lesions known as lymphangioma circumscriptum, and more deep-seated lesions (cavernous lymphangioma and cystic hygroma). They are present at birth, although they may be discovered later in life. They are most commonly located in the neck and axilla, but they also occur in the mouth, arm, mediastinum, lung, abdomen and viscera. Some may appear as a tiny blue or red spot while others are massive and affect an entire arm or leg.[8019 The signs and symptoms vary depending on the size and location of the mass; however, lymphangiomas can disfigure affected areas and disrupt the function of nearby organs or tissues. The exact underlying cause is unknown. Treatment options vary based on the signs and symptoms present in each person but may include surgery.Lymphatic malformations or lymphangiomas are benign (non-cancerous) vascular lesions made of fluid-filled spaces (cysts) thought to occur due to abnormal development of the
Last updated: 6/22/2016
- Lymphatic Malformations. NORD. June 2011; https://www.rarediseases.org/rare-disease-information/rare-diseases/byID/646/viewAbstract.
- Pielop JA. Vascular lesions in the newborn. UpToDate. May, 2016; http://www.uptodate.com/contents/vascular-lesions-in-the-newborn.
- Robert A Schwartz, MD, MPH. Lymphangioma. Medscape Reference. 2016; http://emedicine.medscape.com/article/1086806-overview.
- Lymphatic malformation. DermNet NZ. December 2014; http://dermnetnz.org/vascular/lymphangioma.html.
- Luo CC, Huang CS, Chao HC, Chu SM & Hsueh C. Intra-Abdominal Cystic Lymphangiomas in Infancy And Childhood. Chang Gung Med J. July, 2004; 27(7):http://memo.cgu.edu.tw/cgmj/2707/270704.pdf.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Lymphatic malformations. Click on the link to view a sample search on this topic.