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Diseases

Genetic and Rare Diseases Information Center (GARD)

Catastrophic antiphospholipid syndrome


Other Names for this Disease
  • Catastrophic antiphospholipid antibody syndrome
  • Thrombotic storm
Related Diseases
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Overview

Catastrophic antiphospholipid syndrome (CAPS) is a rare form of antiphospholipid syndrome (APS). In CAPS multiple blood clots form throughout the body over a short period of time (usually within a week). CAPS is a medical emergency, as clots can cause life-threatening multi-organ failure. The cause of CAPS is unknown. A widely accepted explanation is that it is caused by a combination of gene mutations (making one more susceptible to CAPS) and an environmental trigger, such as an infection, trauma, or surgery.[1]
Last updated: 5/25/2016

References

  1. Erkan D. Top 10 Points Patients Should Know About Catastrophic Antiphospholipid Syndrome. Hospital for Special Surgery. Last reviewed April 28, 2016; https://www.hss.edu/conditions_top-ten-points-for-patients-catastrophic-antiphospholipid-syndrome.asp. Accessed 5/25/2016.
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Basic Information

Selected Full-Text Journal Articles

Other Names for this Disease
  • Catastrophic antiphospholipid antibody syndrome
  • Thrombotic storm
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.