March 13, 2018
NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) caused by mutations in a gene called C9orf72. The results of the search, published in Nature Genetics, uncovered a new set of genes that may hasten neuron death during the disease.
Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1
Juvenile amyotrophic lateral sclerosis