This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
Autoimmune disorder[ more ]
|Congestive heart failure||
Heart failure[ more ]
High blood eosinophil count
Red or purple spots on the skin
Inflammation of blood vessel
|30%-79% of people have these symptoms|
Pain in stomach
Stomach pain[ more ]
|Abnormal pericardium morphology||0001697|
|Abnormal pleura morphology||0002103|
Swallowing difficulty[ more ]
Tiredness[ more ]
Impaired gait[ more ]
Blood in urine
Enlarged and thickened heart muscle
|Hypopigmented skin patches||
Patchy loss of skin color
|Nausea and vomiting||0002017|
Blood clot in vein
|5%-29% of people have these symptoms|
Persistent blue color of hands, feet, or parts of face
|Cranial nerve paralysis||0006824|
Acid reflux disease
Heartburn[ more ]
Paralysis or weakness of one side of body
Coughing up blood
Intestinal blockage[ more ]
Muscle pain[ more ]
Inflammation of heart muscle
High urine protein levels
Protein in urine[ more ]
|Recurrent intrapulmonary hemorrhage||
Recurrent bleeding into lungs
Renal failure in adulthood[ more ]
Firm lump under the skin
Growth of abnormal tissue under the skin[ more ]
|Transient ischemic attack||
Learn more orphan products.
If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. You may find these specialists through advocacy organizations, clinical trials, or articles published in medical journals. You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments.
If you can’t find a specialist in your local area, try contacting national or international specialists. They may be able to refer you to someone they know through conferences or research efforts. Some specialists may be willing to consult with you or your local doctors over the phone or by email if you can't travel to them for care.
You can find more tips in our guide, How to Find a Disease Specialist. We also encourage you to explore the rest of this page to find resources that can help you find specialists.
Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.
Conditions with similar signs and symptoms from Orphanet
Differential diagnoses of EGPA include granulomatosis with polyangiitis (formerly Wegener granulomatosis), hypereosinophilic syndrome, microscopic polyangiitis, cryoglobulinemia (see these terms), drug reactions, bronchocentric granulomatosis, fungal and parasitic infections, and malignancy.
Visit the Orphanet disease page for more information.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
My wife was diagnosed with eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome) about 9 years ago but lately she has red itchy rashes and spots on her back, arms and legs. Is that a symptom of Churg Strauss coming back? See answer